Searchable abstracts of presentations at key conferences in endocrinology

ea0022p528 | Male reproduction | ECE2010

Single nucleotide polymorphism (SNP) of endothelial nitric oxide synthase (eNOS) gene (GLU298ASP VARIANT) in infertile men with asthenozoospermia

Buldreghini Eddi , Mahfouz Reda Z , Vignini Arianna , Agarwal Ashok , Balercia Giancarlo

Objective(s): Single nucleotide polymorphism (SNP) in endothelial nitric oxide synthase (eNOS) G894T may affect the oxidative stress–response. Our objective was to examine G894T SNP eNOS genotype frequencies and its potential role with sperm motility in infertile men. Through this prospective controlled study in the Andrology Unit, we have enrolled infertile (n=70) and healthy (n=60) men. Sperm motion kinetics assessed by computer assisted semen analysis (CA...

ea0020p630 | Reproduction | ECE2009

Free thiols in human spermatozoa: correlation with Na+/K+-ATPase, Ca2+-ATPase activities and sperm motility

Vignini Arianna , Buldreghini Eddi , Nanetti Laura , Raffaelli Francesca , Paggi Francesca , Boscaro Marco , Mazzanti Laura , Balercia Giancarlo

The aim of the present study was to measure free thiols content, Na+/K+-ATPase, Ca2+-ATPase activities in human spermatozoa of asthenozoospermic patients and normospermic donors, and evaluate any influence on kinetic sperm features, as well as correlation with peroxynitrite. In fact, membrane integrity and its composition are the basic characteristics of the sperm membrane, thus, it is evident that its composition is an important factor for mem...